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N Engl J Med 326 , 13161322, doi:10.1056/NEJM199205143262003 (1992)

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Patients often experience significant reductions in their blood sugar levels, which can reduce the risk of diabetes-related complications such as cardiovascular disease, kidney problems, and neuropathy

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If the cancer cells penetrate deeper into the skin into the dermis or beyond the diagnosis changes to lentigo maligna melanoma, indicating invasive melanoma

The side effects usually stay mild and just go away without treatment