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Maintenance dose is given as per need

At the maintenance dose of 2.4mg, it lasts barely two weeks

It is important to recognise that symptom severity does not always correlate with the degree of deficiency

Some people may require regular injections to maintain adequate levels for their entire lives, whilst others may just need an initial boost which can then be maintained through diet

Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels

Doses of vitamin B12 exceeding 10 mcg daily may produce a hematologic response in patients who have a folate deficiency