Manages healthy metabolism by helping in weight management efforts
Biochim Biophys Acta 2006
Targeted delivery to peripheral nerves remains challenging due to the blood-nerve barrier, and off-target effects can pose safety risks
For patients inadequately controlled on sitagliptin monotherapy: For patients inadequately controlled on sitagliptin alone, the usual starting dose of SITAGLIPTIN PHOSPHATE + METFORMIN HCl (JANUMET) is 50 mg sitagliptin/500 mg metformin hydrochloride twice daily
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Patients should inform their prescriber about all supplements, herbal products, and over-the-counter medicines they are taking to enable comprehensive safety assessment