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Results Combination treatment with metformin and liraglutide is more effective than single treatment to protect against palmitic acid (PA)-induced endothelial dysfunction In cultured human umbilical vein endothelial cells (HUVECs), PA induced endothelial dysfunction, characterized by increased reactive oxygen species (ROS) production, decreased NO level and reduced intracellular phosphorylated endothelial NO synthase (p-eNOS) protein level, in a concentration-dependent manner (Fig

Therefore, the development of maize varieties tolerant to alkaline stress or the elucidation of the entire mechanism of maize plant responses to alkaline toxicity is essential for sustainable maize production

A study in 13 healthy sleepers found those who showed a preference for right side-sleeping had better sleep quality, as measured by actigraphy and questionnaire, than those who showed a preference for supine (on the back) sleeping

Hepatocytes have no or very low levels of GLP-1R, and studies report no direct effects of GLP-1R agonist on hepatocytes 11

What cardiovascular benefits do GLP-1 medications offer beyond weight loss