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Four weeks after UUO surgery, the mice were euthanized at 14 d

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(2.4) Recommended Starting, Escalation and Maintenance Dosage of RYBELSUS and OZEMPIC Tablets (2.2) RYBELSUS (2.2) Day 1 to 30: Recommended starting dosage is 3 mg orally once daily for 30 days (this dosage is not effective for glycemic control) Days 31 to 60: Increase the dosage to 7 mg orally once daily

The Institutional Review Board (IRB) and Independent Ethics Committee (IEC) approved the study and the informed consent form (CAAE: 42972521.9.0000.9287)