They stimulate insulin secretion and inhibit glucagon secretion by elevating endogenous GLP-1 concentrations without an intrinsic hypoglycaemia risk
This magnitude of improvement matches or exceeds many dedicated diabetes medications
Not a therapeutic dose for weight loss or HbA1c
Sterility risks Injectable medications must be manufactured under highly controlled sterile conditions
Pooled analysis reported statistically significant effect on total stroke outcomes from treatment with GLP-1RA versus placebo [RR=0.83, 95%CI(0.73, 0.95), p =0.005], showed that the risk of total stroke was about 17% lower in the GLP-1RA treatment group than the placebo group
That may require a long-term medication to manage it. If youve lost weight on one of these medications and youre scared to go off it, despite your doctor giving you the okay, Dr