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Importantly, the largest reductions in BMI were observed in the southern United States, which also reported the highest rates of GLP-1 RA dispensing claims (Rader et al., 2024), a geographic concordance that is consistent with a causal contribution of these pharmacotherapies to the observed population-level BMI decline

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Commercial coverage for Wegovy has actually deteriorated: 42% more patients lacked coverage in early 2026 compared to 2025, with over 41 million Americans without access

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Multi-factor logistic regression analysis of these drugs was performed in combination with patient information (Figure 4)