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TRIUMPH-4, the first completed Phase 3 trial, showed 28.7% average body weight loss at 68 weeks on retatrutide 12mg versus 2.1% on placebo, as reported by Eli Lilly in December 2025 (peer-reviewed publication pending)

As shown in Figure S13 , the ignorable variations further demonstrated the favorable biosafety of the NPs

Trends in Sport Sciences, 31(3), 139149

validated, alarmed freezer storage is required in trial settings

[Abstract]2024 Nov 10;43(11):114915

Observational data from anti-aging clinics using this protocol report lean mass increases of 24 kg over 6 months in middle-aged adults maintaining isocaloric diets