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However, there are notable challenges to the use of laccases for proximity labeling technology, most importantly that no laccase has previously been expressed and shown to be active in mammalian cells
TRANSCEND-T2D-1 Phase 3 Study (Lancet, 2026) Study Title: Efficacy and safety of retatrutide in people with type 2 diabetes and inadequate glycaemic control Links: Lancet: [thelancet.com], [thelancet.com] PubMed: [pubmed.ncb...lm.nih.gov] Key Findings: 537 participants enrolled
The mechanisms are different and do not directly conflict, but absence of conflict is not the same as evidence of benefit
In some cases of pernicious anemia, parietal cell auto-antibodies lead to the destruction of IFproducing parietal cells in the stomach resulting in B12 malabsorption, and thus deficiency
In topical skin care products it inhibits melanin synthesis and thus protects against UV damage
Blood 48 (1): 53-62
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