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This causes more hemolysis and vaso-occlusive events, which are disease symptoms

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Crosses the Blood-Brain Barrier Unlike many peptides and growth factors, Dihexa is orally bioavailable and crosses the BBB , meaning it can be taken as an oral tablet and still reach brain tissues in therapeutic concentrations

Moreover, the mammalian target of rapamycin (mTOR) complex family proteins regulates ferroptosis by manipulating SLC7A11 (Xu et al., 2021)