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Although no significant change was observed in the bone formation marker P1NP, the semaglutide group showed a significant increase in the bone resorption marker CTX and a reduction in areal BMD at both the lumbar spine and total hip

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2001 Oct;11(5):266-72

Common side effects (rare): Temporary fatigue in first 3-5 days Mild headaches Injection site redness Increased appetite Vivid dreams (uncommon) Serious side effects (very rare): Allergic reaction to peptide Injection site infection (poor technique) Dizziness or lightheadedness Who shouldn't use BPC-157: Pregnant or breastfeeding women Active cancer diagnosis (promotes angiogenesis) Recent retinal surgery (blood vessel growth in eye) Known allergy to peptides Drug interactions: BPC-157 doesn't interact with most medications, but combining with: NSAIDs: BPC-157 protects against NSAID damage (actually beneficial) Blood thinners: Monitor closely due to angiogenesis effects Immunosuppressants: May reduce BPC-157 effectiveness Dosing mistakes to avoid Get the protocol right from the start

Drink plenty of water throughout the day to help the body efficiently process and utilise the nutrients from the tablet