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Additionally, if you are analyzing plasma amino acids on your patients, the glutamate/(serine + glycine) index developed by Gaggini et al could be a sensitive indicator identifying risk in FLD
Yes, patients should avoid food around dosing time and may need to follow nutritional guidelines to support success
USA 118 , e2005164118 (2021)
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Studies have shown that JAK2 may also phosphorylate insulin receptor substrate 1/2 (IRS1/2) and activate the phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) pathway (Yamauchi et al., 1998
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