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For prescription availability in Canada right now: Tirzepatide is the closest alternative with strong efficacy (20.9%) and an existing prescription pathway

The general rule I was told is if you can't comfortably hold a LiPo pack tightly in your hand after using it, it's way too hot

2022;387(12):1089-1098 and Supplementary Appendix

Divide the total peptide amount by your desired concentration

In obesity, NNMT activity is unusually high in fat cells, which means a lot of nicotinamide gets thrown out before it can be turned into NAD+

However, people with a BMI of 27 or higher may also qualify if they have weight-related health conditions, such as type 2 diabetes or hypertension