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Additional info National Heart, Lung, and Blood Institute (NHLBI) About the Reviewer Howard E

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B., Perera, G

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A deep joint infection in a reconstructed or replaced knee is one of the most serious complications in orthopaedics

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The patience required during dose escalation is actually one of the most valuable aspects of the protocol

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Angiogenic, anti-inflammatory, and neuroprotective effects have all been documented across multiple preclinical delivery routes

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These differences likely reflect local tissue binding, lymphatic uptake, and first-pass metabolism variations between administration sites and species

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