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Digestion Compromised digestion can be an underlying factor, especially of autoimmune thyroid disease such as Hashimotos Thyroiditis, due to the association with increased intestinal permeability (Leaky Gut). 8 This is often mediated by gluten, 9 imbalanced gut bacteria, 10 and stress, 11 which drives autoimmunity, especially if an individual is genetically susceptible. 12 If food is also poorly digested, say from eating on the go, and moves through the gut too fast due to diarrhoea, nutrient absorption becomes harder

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Therefore, selenium deficiency is associated with thyroid dysfunction and increased risk of thyroid autoimmunity and nodules [65], a condition further aggravated by the fact that concurrent iodine and selenium deficiency is rather common [66, 67]

For the latest on Phase 3 TRIUMPH trial progress, see our Retatrutide 2026 Phase 3 Update

The synthetic peptide FOX04-DRI selectively disrupts this interaction, thereby restoring the apoptotic activity of p53 and leading to the elimination of senescent cells