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A negative regulator of MAP kinase causes depressive behavior
GLP-1 RAs also improve glucose uptake and utilization, ensuring energy stability even in metabolically challenged neurons (92)
The action of estradiol is primarily directed by interaction with the estrogen receptor (ER) nuclear receptors (alpha and beta) in peripheral target tissues further modulated via feedback by GH and IGF-1 (Veldhuis et al., 2006)
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