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These medications can help some patients feel full sooner, reduce food noise, improve portion control, support blood sugar regulation, and lose meaningful weight when used with medical supervision
While the study clarifies some conflicting findings on NVAMD risk in adults taking GLP-1s for type 2 diabetes, Cai warns that her groups findings should not be applied to other groups, such as people taking GLP-1 drugs primarily for weight loss, and additional research should be done in people without type 2 diabetes
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In a rat model of neuropathic pain induced by tight ligation of L5/L6 spinal nerves, morroniside, administered either orally or intrathecally, dose-dependently alleviated mechanical allodynia, with comparable maximal efficacy (E max ) and an effective dose 50% (ED 50 ) values of 335 mgkg (oral) and 7.1 g (intrathecal) [73]
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