Note: Retatrutide is still in clinical trials and not FDA-approved to treat obesity or for weight loss
Wegovy (semaglutide 2.4 mg) is a glucagon-like peptide-1 (GLP-1) receptor agonist licensed by the MHRA for weight management in adults with obesity or overweight with weight-related comorbidities
The medication does not permanently reset metabolic function or appetite regulation, which is why a structured approach to discontinuation and long-term lifestyle modification is critical for maintaining weight loss achievements
Zepbound has been approved for a specific population adults with obesity or those who are overweight and have at least one weight-related condition, such as high blood pressure, Type 2 diabetes or high cholesterol
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It is possible that, in addition to factors such as reduced alcohol consumption, weight loss-related improvements in body image, or relief associated with better glycaemic control in diabetes, there may also be direct neurobiological mechanisms involved for example, through changes in the functioning of the brains reward system. Read the report in The Lancet Psychiatry Read more about type 2 diabetes I would like to make a regular donation of
