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Switching to the oral small molecule glucagon-like peptide-1 (GLP-1) orforglipron after taking injectable GLP-1s helped patients maintain mostbut not allof their weight loss, according to a clinical trial led by Weill Cornell Medicine and NewYork-Presbyterian investigators

PubMed Kinesya E, Santoso D, Gde Arya N, et al

This is the logic behind putting protein and resistance training at the top of the hierarchy and using creatine to support the training that protects muscle: you are not just losing weight, you are trying to keep the parts of your body you want to keep

Hamadi SA, Mohammed MM, Aljaf AN, Abdulrazak A

Researchers should consult the applicable Certificate of Analysis for lot-specific purity, identity, and testing data

Hormones, appetite regulation and metabolism all play a role