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The drug increases insulin secretion by glucose-dependent insulin synthesis and in vivo secretion of insulin from pancreatic beta cells in the presence of elevated glucose levels
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At the highest doses used for obesity treatment (2.4 mg semaglutide, 15 mg tirzepatide), the medication may overwhelm certain regulatory mechanisms and produce paradoxical sensitization
A number of musicians and actors told the Guardian that they personally knew high-profile people in their industries using Ozempic, although none would go on record
Temperature of medication Unused semaglutide must be refrigerated between 36 and 46 degrees Fahrenheit and then can be stored at room temperature after its first use
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