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Serious events (like severe pancreatitis or major liver issues) have been rare and similar to placebo so far, but long-term safety is still being monitored in ongoing phase 3 programmes
Most patients tolerate weekly 0.25mg increments better than larger jumps
But efficacy data from trials reflects population averages individual responses vary significantly, and there are multiple valid reasons to make this change
Weight loss with the new oral form of these medications seems to be a bit smaller more like 10% in initial trials but the science is moving fast, and new versions of these drugs are being developed all the time
Independent third-party testing is performed on every lot
Exercise not only helps burn calories but also builds muscle mass, which can increase metabolic rate
