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GLP2 once weekly for the treatment of obesity
PMID: 2180829
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This substitution may increase the half-life of the peptide by protecting it from enzymatic cleavage and degradation
However, major changes on the scales are more likely to build after several weeks or months
Balancing the Risks and Benefits In clinical practice, the potential for mild digestive discomfort (including occasional heartburn) should always be weighed against the profound benefits Wegovy offers: Sustained, clinically meaningful weight loss: Patients in major studies achieved an average of around 15% reduction in body weight over 68 weeks, outperforming many other weight-management medications
