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This research was funded by the Fundamental Research Business Expenses of the Central Universities, grant number 2024GCZX002
Its 2022 disclosure by Coskun and colleagues (Cell Metabolism) marked a deliberate extension of the dual-incretin agonist concept pioneered by tirzepatide, adding glucagon receptor engagement to the pharmacological palette
In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin
Tirzepatides pivotal trials span diabetes, obesity, and sleep apnea
If youre pregnant, have certain health conditions (like kidney disease or blood disorders), or are already taking supplements, your doctor might suggest a different approach