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Some employers add prescription opioids, benzodiazepines, or specific substances of concern

Starting tirzepatide at the lower end of the equivalent dose range and titrating up is recommended to improve tolerability

These reports vary widely in severity and timing, with some patients noting symptoms shortly after starting the medication or following dose increases, while others report intermittent or persistent discomfort throughout treatment

Coveleski et al

Karsdal MA, Byrjalsen I, Riis BJ, Christiansen C

There is promising research suggesting that GLP-1 drugs may have a positive impact on fertility, particularly for women with insulin resistance and PCOS