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So this is a growing threat that I think needs to be monitored closely. If GLP-1s do become prohibited, athletes could theoretically apply for a therapeutic use exemption (TUE), which allows them to take a drug if it is treating a legitimate medical condition, and does not meaningfully enhance their performance
Others come to it from wound-healing, connective-tissue, or barrier-model work where inflammation and remodeling are both part of the endpoint
Fasting insulin and the homeostatic model assessment (HOMA-IR, derived from fasting glucose and insulin) are the most common and practical surrogates, and they are the measures that move so dramatically in the retatrutide trials
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