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The author declares that there are no conflicts of interest
More evidence is needed to determine what effect, if any, antioxidants such as alpha-lipoic acid have on chemotherapy
Diagnostic markers and potential therapeutic targets for GCs are urgently needed
Hum Mol Genet 29
Abbreviations AD: Alzheimers disease ALS: Amyotrophic lateral sclerosis AMPK: AMP-activated protein kinase BBB: Blood-brain barrier CNS: Central nerve system EAAT-1: Excitatory amino acid transporter 1 EAE: Experimental allergic encephalomyelitis H 2 O 2 : Hydrogen peroxide MCI: Mild cognitive impairment MS: Multiple sclerosis MSU: Monosodium urate mTOR: Mammalian target of rapamycin NO: Nitric oxide ONOO : Peroxynitrite PD: Parkinsons disease RNS: Reactive nitrogen species ROS: Reactive oxygen species SCI: Spinal cord injury SOD: Superoxide dismutase TFEB: Transcription factor EB TLR: Toll-like receptor UA: Uric acid VEGF: Vascular endothelial growth factor XO: Xanthine oxidase References Burtscher J, Millet GP, Place N, Kayser B, Zanou N
These can include: Nausea Vomiting Diarrhea or constipation Abdominal pain Most providers start patients on a very low dose and gradually increase it over several months
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