An exploratory sub-analysis of the PIONEER 8 study evaluated the impact of background insulin (basal, premixed, or basal-bolus) with or without metformin on the efficacy and safety of oral semaglutide
Semaglutide and diet Healthy eating and exercise are recommended when taking semaglutide, regardless of whether youre taking the oral or injectable version
FDA Warning Letters and Shortage Resolution The FDA sent 30 warning letters to GLP-1 compounders on February 20, 2026, made public March 3, 2026
The MHRA issued a warning about the risk of acute pancreatitis in January, which is often linked to gallstones, a common side effect of GLP-1s
Its pathogenesis is unknown
Developing contingency plans for supply interruptions, including knowing alternative pharmacy options and maintaining communication with prescribing providers, is recommended for patients taking temperature-sensitive medications