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Retatrutide vs Tirzepatide vs Semaglutide: Dosage Comparison All three peptides use once-weekly subcutaneous dosing, but the dose ranges, titration schedules, and maintenance doses differ significantly
Tilt head back slightly, spray into each nostril, avoid blowing nose immediately after, and use consistently at the same times daily for optimal absorption
GLP-1 is thought to act in the central nervous system to regulate feeding behaviour and on pancreatic beta cell GLP-1 receptors (GLP-1Rs) to stimulate insulin secretion
Warning: Semaglutide will not be prescribed to anyone with the following conditions: BMI under 27, eating disorder, gallbladder disease, drug or alcohol abuse, recent bariatric surgery, pancreatitis, medullary thyroid cancer, currently pregnant or breastfeeding, planning to become pregnant, diabetic retinopathy, multiple endocrine neoplasia type 2, or a family history of medullary thyroid carcinoma.