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IMC also prevented diet-driven hepatic cholesterol accumulation and caused both upregulation of the host hepatic bile acid synthetic enzyme CYP7A1 and altered the expression of hepatic genes critical for bile acid feedback regulation

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When administered to rats within 30 minutes of experimental acetaminophen intoxication, 200 mg/kg of curcumin prevented the microscopic appearance of kidney damage, prevented elevations in renal lipid peroxidation, and maintained glutathione levels compared to control rats (Cekmen 2009)