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The parent protein was identified during investigations of compounds in human gastric juice that conferred protection against ulceration, and the active 15-residue fragment retained the full activity of the larger protein in subsequent characterisation studies
AAR Conceptualization (supporting), Methodology (supporting), Supervision (equal), Writing-reviewing and editing (equal)
Even individuals with a healthy BMI may benefit from microdosing GLP-1s
xi Julius M
doi: 10.2337/dc11-s227 8 BrownJCPedersonRAJorpesEMuttV
For example, medical conditions were self-reported, whereas Bessette and Anderson were unable to measure all trial exclusion criteria with accurate temporality, which may underestimate the proportion excluded. Bessette said that primary care providers should consider screening for depression, liver function, and concomitant use of medications that delay gastric emptying before prescribing medications like GLP-1 receptor agonists
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