1) from 3,4- cis -leucoanthocyanidins ( 2 ) to anthocyanidins ( 3 ) is thought to be catalysed by the Fe/-ketoglutarate-dependent dioxygenase leucoanthocyanidin dioxygenase (LDOX), also called anthocyanidin synthase (ANS) 8,9
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The mice they used have a mutation in the gene superoxide dismutase 1 (SOD1) which causes them to develop a condition which is similar to that of human ALS
Younossi ZM, Golabi P, Paik JM, Henry A, Van Dongen C, Henry L
& Pascual, A