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81 Additionally, DLST-mediated succinylation of PDHA1 at K83 enhances PDH activity and -KG accumulation, which activates OXGR1MAPK/ERK signaling in TAMs, suppressing MHC-II expression and T-cell priming

This injury-repair response evolves gradually over time, hence the slow onset of symptoms

Significant improvement typically requires three to six sessions for moderate scars, potentially eight to ten sessions for severe scarring

Together, they address tissue repair from multiple angles simultaneously

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