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Yue X, et al

With the empirical evidence of intestinal factors affecting osteoporosis, the mechanisms of how the intestinal intrinsic structure, gut microbiota, and microbial metabolites interact with bone health have been increasingly elucidated

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When injected into facial muscles, they induce temporary paralysis, halting muscle contractions and thereby relaxing and softening wrinkles

Experimental literature explores its interaction with laboratory models of cell cycle regulation and peptide-mediated processes

Discussion We report a large-scale GWAS of treatment response to GLP1 medications and identify a missense variant in GLP1R , which encodes the therapeutic target of semaglutide and tirzepatide that associates with BMI loss