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AIDS 2004;18:1549-60
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As a result, there is an increased insulin secretion in the pancreatic -cells and suppression of glucagon release
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A high-fat diet induces the expression of the ketogenic enzyme mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase (mhMGCs) in jejunal tissue and the production of functional ketones, which act on the fatty acid/ketone receptor FFAR3 expressed in the small intestinal epithelium to inhibit GLP-1 secretion (50)
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