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found that 37.5% of participants completed 12 injections compared to 18.7% in the placebo group, suggesting modest efficacy

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found that epithalon can, when administered to both elderly monkeys and people, modulate the functional state of the pineal gland, which secretes melatonin to control the circadian cycle and wakefulness [8]

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Doses were inconsistent, side effects showed up more often than expected, and in some cases, the risks were serious enough to outweigh any potential benefits