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This regulatory pathway exists specifically to serve patients who need customized doses, alternative formulations, or medications in short supply
Treatments are normally about 1 week apart
In the phase 3 ACHIEVE-3 trial , adults with type 2 diabetes inadequately controlled by metformin were randomized to receive orforglipron or oral semaglutide (7 mg and 14 mg, doses approved for type 2 diabetes)
Most people don't notice this happening
However, while the Kendalls correlation is frequently thought to be more robust to outliers, particularly for small sample sizes like this data-set
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