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short sequential cohort about -4.7% during the initial 2.5 mg phase and -12.7% by the end of the 5 mg phase (Barrea EXCLI Journal 2026)

It was not drug approval, and the FDA has not made a final decision

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Clinically, keeping the patient calm and, if necessary, administering a benzodiazepine is recognized as a safe and sufficient measure to reduce blood pressure to a safe and stable range without inducing organ hypoperfusion (Grossman et al, 2005