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Gene expression levels were standardized using the z score method, and cluster analysis of DEGs in key pathways was performed using the pheatmap R package [33] based on standardized FPKM values
Administration: Divided into two daily doses (morning and evening)
Hepatic lipid assays: Ex vivo hepatic tissue studies and hepatocyte cell-line work have documented retatrutide's effect on markers associated with non-alcoholic fatty liver models, including lipid droplet accumulation and markers of hepatic lipid flux
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The mechanism of triacylglycerol accumulation in the liver of myo-inositol-deficient rats Biochim Biophys Acta 1974
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