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First, because tesamorelin raises IGF-1, its label carries GH-class cautions contraindications in active malignancy and pregnancy, and glucose monitoring even though the trials did not show significant glycemic worsening
Less urgent but still worth reporting: side effects that do not improve after seven days at any dose level, persistent diarrhea that interferes with daily activities, significant hair thinning (which can occur during rapid weight loss phases and may relate to nutritional deficiencies rather than medication directly), mood changes including increased anxiety or depression, and hair loss patterns that seem disproportionate to weight loss speed
The AAD also notes lasers as a safe, painless option that requires ongoing sessions to maintain gains
Rothman KJ, Gallacher JE, Hatch EE
In clinical studies with adults with type 2 diabetes, Bydureon BCise lowered A1C by an average of 1.1 to 1.4% from an average starting A1C of 8.4 to 8.5%
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