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Unlike steroids, peptides are hydrophilic and bind to surface receptors such as G-protein-coupled receptors (GPCRs) to trigger internal signaling cascades without entering the cell nucleus

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Krashia P, Cordella A, Nobili A, La Barbera L, Federici M, Leuti A, et al

A study found that physically active older adults had higher glutathione concentrations than their sedentary peers