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The first coprimary endpoint was weight loss of 5% or greater from baseline, which was achieved in 83.3% of the semaglutide group vs

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The researchers concluded that there was small improvement, but due to the limited number of patients in the study, firm conclusions could not be drawn

A study published in the Journal of the Endocrine Society reported as early as 2021 that participants lost about 9-10% of their lean muscle mass while taking semaglutide

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