Charbonnel B, Steinberg H, Eymard E, Xu L, Thakkar P, Prabhu V, et al
Obese and lean mice were given either saline, AOD9604, or hGH through an osmotic pump over the course of 14 days
The drug met the primary and key secondary endpoints, delivering superior A1C reduction and weight loss at 40 weeks compared to placebo
Historically, a significant barrier to access has been the prohibitive cost of GLP-1 medications, particularly for patients without Type 2 diabetes
A lower starting dose gave the body more time to adjust
But it is a powerful, evidence-based tool for people who want: Appetite control without injections Weight loss without hormone manipulation A natural alternative to GLP-1 medications A sustainable, habit-based solution And most importantly: guidance from a clinician who looks at your whole health, not just the scale