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As it has a significant role in restricting the entry of blood-derived neurotoxins, pathogens, and other damaging components from the peripheral vasculature into the brain, there is ongoing investigation into the interplay between BBB permeability and neurodegeneration (Daneman and Prat, 2015
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[17] [18] Anti-Inflammatory and Antioxidant A study demonstrated that BPC-157 is a powerful antioxidant by reducing free radical formation via the Nitric Oxide system, attenuating duodenal lesions in rats by significantly decreasing oxidative stress
Moreover, intersections between upregulated DEGs in the control group and downregulated DEGs in the treatment groups, as well as between downregulated DEGs in the control group and upregulated DEGs in the treatment groups, also demonstrated that the combination group had a greater overlap with the control group than either single-drug group did (Additional file 2: Figure S5)
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