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Rights and permissions About this article Cite this article Shain, A., Bastian, B

Apr 03 2013;309(13):1359-1367

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Other notable adverse effects include injection site reactions (redness, itching, or swelling at the injection site), fatigue, and decreased appetite

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Nel 2019 stato avviato il trial FLOW ( Effect of Semaglutide Versus Placebo on the Progression of Renal Impairment in Subjects With Type 2 Diabetes and Chronic Kidney Disease ) [59], che ha reclutato 3508 pazienti al fine di valutare la capacit di semaglutide di ridurre lincidenza dellendpoint primario composito (declino del eGFR 50% rispetto al basale, necessit di dialisi, morte per cause renali, morte per malattia cardiovascolare) rispetto al placebo