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Quick Answer: GLP-1 receptor agonist-related fatigue likely results from multiple indirect mechanisms including substantial caloric restriction, gastrointestinal side effects causing dehydration and nutritional deficits, and metabolic adaptation during weight loss, rather than a single direct pharmacological effect
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In a trial that enrolled 20 pet dogs with idiopathic inflammatory bowel disease, administration of a commercially available probiotic (VSL#3) in amounts providing 112.5125 billion colony forming units (CFUs) per 10 kg body weight per day for 60 days led to a significant decrease in clinical and histological scores
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