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It demonstrates powerful anti-inflammatory properties through melanocortin receptor modulation
This structural effect on neural architecture is what distinguishes Dihexa from most nootropics, which act primarily through neurotransmitter modulation
Evidence boundary The largest Phase 2b trial used oral dosing for 24 weeks and did not show statistically significant weight loss versus placebo
Critical insights from clinical research include the finding that weight loss efficacy is independent of side effects, with less than 1% of weight reduction attributable to gastrointestinal symptoms
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