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Anti-Aging Effects: Helps protect cells from age-related damage and supports DNA repair

In rat pinealocytes (the melatonin-producing cells of the pineal gland), Epitalon was shown to upregulate both AANAT (arylalkylamine N-acetyltransferase, the rate-limiting enzyme in melatonin production) and pCREB (a transcription factor involved in melatonin gene expression)

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

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Kameyama K, Lee HK, Bear MF, Huganir RL (1998)