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Consortium TU (2023) UniProt : the universal protein knowledgebase in 2023

In the human liver, -tocopherol is the form of vitamin E that is preferentially bound to -tocopherol transfer protein (-TTP) and incorporated into lipoproteins that transport -tocopherol in the blood for delivery to extrahepatic tissues

Though vitamins can be found naturally in foods, some body processes make them hard to absorb, and deficiencies can occur

Nat Cell Biol 28 , 848849 (2026)

7.3 Hepatic oxidative stress and the protective role of Nrf2 signaling A key aspect highlighted in this review is the central role of the Nrf2-Keap1-ARE signaling pathway as a major regulator of the hepatic antioxidant response