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The AMPK/ULK1 pathway plays a central role in driving autophagy, while fasting also helps restore lysosomal function and supports effective autophagosome-lysosome fusion, ensuring proper autophagic flux and cellular homeostasis
10.1016/j.neuron.2015.01.019 30 QinZ.FisherG
We observed an increase in survival of infected flies with overexpression of cytosolic antioxidant enzyme superoxide dismutase 1 (SOD1) with two distinct transgenic lines (Figure 4C, 4C, S4B, S4B) and a minimal effect of overexpression of mitochondrial SOD2 (Figure 4C, S4C)
GSH acts as a radiation protector
A total of 39 patients were tested ( n = 19 controls
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