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Factors contributing to success include: Eliminates all the dark areas

10.1016/j.biocel.2006.06.004 61 IsacchiB.FabbriV.GaleottiN.BergonziM

Zhou X, Zhu Y, Liu J, Liu J

Late 20272028: typical FDA review after filing, then possible approval and staggered international filings

That's the reason the North Carolina State Health Plan Board of Trustees voted last year to end coverage of GLP-1s for state employees, after then-North Carolina Treasurer Dale Folwell's office estimated in 2023 that the drugs were projected to cost the State Health Plan $1 billion over the next six years

NICE recommends review of patients on GLP-1 receptor agonists at 6 months to assess efficacy, tolerability, and ongoing appropriateness of treatment